![]() ![]() Copper (EHC 2. 00, 1. INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY. ENVIRONMENTAL HEALTH CRITERIA 2. COPPER. This report contains the collective views of an international group. United Nations Environment Programme, the. International Labour Organisation, or the World Health. Organization. Dameron and colleagues at the. National Research Centre for Environmental Toxicology, Australia. Mr P. D. Howe, Institute of Terrestrial Ecology, Monks Wood. United Kingdom. Published under the joint sponsorship of the United Nations. Environment Programme, the International Labour Organisation, and. World Health Organization, and produced within the framework of. Inter- Organization Programme for the Sound Management of. Chemicals. Errors and omissions excepted, the. SUMMARY AND CONCLUSIONS1. Identity, physical and chemical properties. Analytical methods. Sources of human and environmental exposure. ![]() Environmental transport, distribution and transformation. Environmental levels and human exposure. Kinetics and metabolism in laboratory animals and humans. Effects on laboratory animals and in vitro test systems. Effects on other organisms in the laboratory and field. Environmental effects. IDENTITY, PHYSICAL AND CHEMICAL PROPERTIES AND ANALYTICAL. METHODS. 2. 1. Physical and chemical properties. Analytical methods. Coliena Rentmeester The glass-enclosed stairwells at Hotel Il Parador. From Hawaii to Zanzibar, we've searched the globe for stylish getaways just steps from the sand. Best-Rated HCG Drops for Weight Loss. We answer all your questions about HCG drops, and which diet drops brands are best in the market. Type or paste a DOI name into the text box. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi. Express Helpline- Get answer of your question fast from real experts. Sampling and sample preparation. Sampling. 2. 3. 1. Separation and concentration. Sample preparation. Detection and measurement. Gravimetric and colorimetric methods. Atomic absorption, emission and mass. Specialized methodologies. Speciation in water and sediments. Detection and quantification. Speciation in biological matrices. SOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE3. Anthropogenic sources. Production levels and processes. ENVIRONMENTAL TRANSPORT AND DISTRIBUTION4. INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY ENVIRONMENTAL HEALTH CRITERIA 200 COPPER This report contains the collective views of an international group. RESPIRATORY DISEASE Ed Friedlander, M.D., Pathologist scalpel. Ordinary e-mails are welcome. Baker, Stephen Heifetz, Philip S. In our 157th episode of the Steptoe Cyberlaw Podcast, Stewart Baker, Stephen Heifetz, and Philip. ![]() Transport and distribution between media. Water and sediment. Sewage sludge inputs to land. Biodegradation and abiotic degradation. Aquatic invertebrates. Terrestrial plants. Terrestrial invertebrates. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE5. Environmental levels. Water and sediment. Biota. 5. 1. 4. 1 Aquatic. Terrestrial. 5. 2. General population exposure. Food and beverages. Drinking- water. 5. Organoleptic characteristics. Copper concentrations in. Miscellaneous exposures. Occupational exposures. Total human intake of copper from all environmental. KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS6. Cellular basis of homoeostasis. Absorption in animals and humans. Transport, distribution and storage. Methods of studying homoeostasis. Analytical methods. Biochemical basis of copper toxicity. Interactions with other dietary components. Protein and amino acids. Phytate and fibre. Other interactions (molybdenum, manganese. EFFECTS ON LABORATORY MAMMALS AND IN VITRO TEST SYSTEMS7. Short- term exposure. Inhalation. 7. 2. Copper(II) sulfate. Copper chloride. 7. Repeated exposure: subchronic toxicity. Oral. 7. 3. 1. 1 Copper(II) sulfate. Copper chloride. 7. Long- term exposure chronic toxicity or carcinogenicity. Reproductive and developmental toxicity. Mutagenicity and related end- points. Copper sulfate. 7. In vitro. 7. 6. 1. In vivo. 7. 6. 2. Other copper compounds. In vitro. 7. 7. Neurotoxicity. Copper sulfate. 7. Copper chloride. 7. Immunotoxicity. 7. Copper(II) sulfate. Biochemical mechanisms of toxicity. General population: copper deficiency and toxicity. Copper deficiency. Clinical manifestations of copper deficiency. Biological indicators of copper deficiency. Toxicity of copper in humans. Repeated oral exposures. Gastrointestinal and hepatic effects. Reproduction and development. Cancer. 8. 3. 3. Disorders of copper homoeostasis: populations at risk. Hereditary aceruloplasminaemia. Indian childhood cirrhosis. Idiopathic copper toxicosis, or non- Indian. Chronic liver diseases. Copper in infancy. Malabsorption syndromes. Parenteral nutrition. Haemodialysis patients. Cardiovascular diseases. Occupational exposure. EFFECTS ON OTHER ORGANISMS IN THE LABORATORY AND FIELD9. Bioavailability in water. Predicting effects of copper on fish. Bioavailability of metals in sediments. Plants. 9. 2. 2. 1 Aquatic plants. Terrestrial plants. Toxic effects: laboratory experiments. Microorganisms. 9. Water. 9. 3. 1. 2 Soil. Aquatic organisms. Plants. 9. 3. 2. 2 Invertebrates. Vertebrates. 9. 3. Model ecosystems and community. Terrestrial organisms. Plants. 9. 3. 3. 2 Invertebrates. Vertebrates. 9. 4. Field observations. Aquatic organisms. Terrestrial organisms. Tolerance. 9. 4. 3. Copper fungicides and fertilizers. EVALUATION OF HUMAN HEALTH RISKS AND EFFECTS ON THE ENVIRONMENT1. Concepts and principles to assess risk of adverse effects. Human health risks. Homoeostatic model. Evaluation of risks to human health. Exposure of general population. Occupational exposures. Essentiality versus toxicity in humans. Risk of copper deficiency. Risk from excess copper intake. General population. Occupational risks. Evaluation of effects on the environment. Concept of environmental risk assessment. Components of risk assessment process. Environmental risk assessment for copper. Aquatic biota. 1. Overview of exposure data. Overview of toxicity data. Terrestrial biota. Overview of exposure data. Plant foliar levels. Assessment of toxicity of copper in. CONCLUSIONS AND RECOMMENDATIONS FOR PROTECTION OF HUMAN HEALTH. AND THE ENVIRONMENT. Environmental protection. Health protection. Environmental protection. PREVIOUS EVALUATIONS BY INTERNATIONAL BODIES. RESUME ET CONCLUSIONS. RESUMEN Y CONCLUCIONES. NOTE TO READERS OF THE CRITERIA MONOGRAPHS. Every effort has been made to present information in the criteria. The EHC. monographs have become widely established, used and recognized. PCS/9. 0. 6. 9, Geneva, World. Health Organization). The selection of chemicals has been based on the. Observers do not. Task Group members. Such a procedure ensures the transparency and. Culver, retired from Department of Medicine, University. Califomia, Califorma, USA. Professor H. Dieter, Institute for Water, Soil and Air Hygiene. Federal Enviromnent Agency, Berlin, Germany. Dr R. Erickson, US Environniental Protection Agency, Duluth. Minnesota, USA. Dr G. S. Fell, Department of Pathological Biochemistry, University. Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland. Dr J. Fitzgerald, Environmental Health Branch, Public and. Envircumental Health Service, South Australian Health Commission. Rundle Mall, Adelaide, South Australia, Australia. Dr T. M. Florence, Centre for Environmental Health Sciences, Oyster. Bay, New South Wales, Australia. Professor J. L. Gollan, Brigham and Women's Hospital, Harvard Medical. School, Gastroenterology Division, Boston, Massachusetts, USA. Dr R. A. Goyer, University of Western Ontario, Chapel Hill, North. Carolina, USA ( Chairman). Professor T. C. Hutchinson, Trent University, Environmental and. Resource Studies Program, Peterborough, Ontario, Canada. Ms M. E. Meek, Health Protection Branch, Environmental Health. Directorate, Health Canada, Ottawa, Ontario, Canada. Professor MR. Moore, National Research Centre for Environmental. Toxicology, The University of Queensland, Coopers Plains. Queensland, Australia ( Co- Vice- Chairman). Professer A. Oskarsson, Department of Food Hygiene, Faculty of. Veterinary Medicine, Swedish University of Agricultural Sciences. Uppsala, Sweden. Dr S. Sethi, Department of Pathology, Lady Hardinge Medical College. S. M. T. Sucheta Kripalani Hospital, New Delhi, India. Dr K. H. Summer, National Research Centre for Environment and. Health, Institute of Toxicology, Neuherberg, Germany. Dr J. H. M. Terninink, Department of Toxicology, Wageningen Agricultural. University, Wageningen, The Netherlands ( Co- Vice- Chairman). Dr R. Uauy, University of Chile, Santiago, Chile. Dr J. M. Weeks, Institute of Terrestrial Ecology, Monks Wood. Abbots Ripton, Huntingdon, Cambridgeshire, United Kingdom. Dr W. J. Adams, Kennecott Utah Copper, Magna, Utah, USA (Representing. Dr K. Bentley, Department of Health and Family Services, Environmental. Health Policy, Canberra, Australia. Dr K. J. Buckett, Environmental Health Service, Health Department. Western Australia, Perth, Western Australia, Australia. Professor J. C. Castilla, Ecology Department, Faculty of Biological. Sciences, Pontificia Universidad Catolica de Chile, Santiago, Chile. Representing the Chilean Govemment). Dr C. Fortin, Commercial Chemicals Evaluation Branch, Environment. Canada, Ottawa, Ontario, Canada. Dr R. Gaunt, RTZ Ltd, London, United Kingdom (Representing the. European Centre for Ecotoxicology and Toxicology of Chemicals). Mr M. Thierry Gerschel, Tref. Imray, Environmental Health Branch, Queensland Health. Brisbane, Queensland, Australia. Mr C. M. Lee, International Copper Association, New York, USA. Dr E. V. Ohanian, Health and Ecological Criteria Division, Office of. Water, US Environinental Protection Agency, Washington, DC, USA. Dr J.- P. Robin, Noranda Metallurgy lue., Occupational Health & Safety. Mc. Gill College, Montreal, Quebec, Canada (Representing ICME). Secretariat. Dr G. C. Becking, International Programme on Chemical Safety. Inter- regional Research Unit, World Health Organization, Research. Triangle Park, North Carolina, USA ( Secretary). Mr P. Callan, Departrnent of Health and Family Services, Environmental. Health Policy, Canberra, Australia) ( Co- rapporteur). Dr C. Dameron, National Research Centre for Environmental Toxicology. The University of Queensland, Coopers Plains, Queensland, Australia. Mr P. D. Howe, Institute of Terrestrial Ecology, Monks Wood, Abbots. Ripton, Huntingdon, Cambridgeshire, United Kingdom ( Co- rapporteur). Dr L. Tomaska, Australian and New Zealand Food Authority, Canberra. Australia ( Co- rapporteur). WHO TASK GROUP ON ENVIRONMENTAL HEALTH CRITERIA FOR COPPER. A WHO Task Group on Enviromnental Health Criteria for Copper met. Brisbane, Australia, from 2. June 1. 99. 6. The meeting was. Australian Commonwealth and State. Govemments through a national steering committee chaired by Dr K. Participants were welcorned by Dr G. R. In opening the meeting, Dr G. C. Becking, on behalf. Dr M. Mercier, Director of the IPCS and the three cooperating.
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